The classical approach to understand the structure and function of the human body is based on anatomical dissection. This approach has gained much information about the global muscles of the body. Recent emphasis is on the deep core muscles and their roles in dynamic joint stability. The focus of this seminar is to target this current issue. The structure and function of the spines will be discussed in terms of morphology, biomechanics and motion analysis. Clinical evaluation, therapeutic exercise, surgical intervention, and biomechanical model will be reviewed and discussed in the form of case study.